An injury disturbs the tissue homeostasis and activates the innate immune system leading to the recruitment of several immune cells at the site of injury. These immune cells secrete cytokines, growth factors, and enzymes to establish an inflammatory milieu.

Description

Advances in Physiological Sciences, Volume 26: Homeostasis in Injury and Shock covers the proceedings of Homeostasis in Injury and Shock, which is a satellite symposium of the 28th International Congress of Physiological Sciences.
This book discusses several studies that are relevant in understanding the nature of injury and shock. Topics include thermoregulation after trauma; neuroendocrine responses to injury and shock; and effect of injury and infection on visceral metabolism and circulation.
Medical practitioners will find great interest in this book, since it covers the physiological implications of tissue damage.

Table of Contents

Foreword

Acknowledgments

Invited Lectures

The Brain in Shock

Thermo-Regulation after Trauma

Neuro-Endocrine Responses to Injury and Shock

Discussion

Effect of Injury and Infection on Visceral Metabolism and Circulation

Carbohydrate Metabolism after Injury. The Development and Maintenance of Hyperglycaemia

Sympatho-Adrenal and Local Control of Adipose Tissue Function in Injury and Shock

Plasma Protein Concentration after Injury - A Simple Computer Model

Discussion

Cardiovascular Reflexes after Injury

Control of Coronary Vascular Tone in Hemorrhagic Shock

The Effect of Injury on the Micro-circulation

Discussion

Plasma Catecholamines in Emergency Situations

Endorphin Involvement in the Pathophysiology of Shock and Trauma: Therapeutic Effects of Naloxone

Discussion

Altered Insulin Sensitivity in Endotoxin and Septic Shock

Evaluation of the Role of Catecholamines in Altering Glucose Metabolism after Injury

Liver Glycogen Phosphorylase, Catecholamines and Stress

Discussion

Interrelations of RES Endocytic and Exocytic Functions with Glucose Homeostasis in the Pathogenesis of Endotoxin Shock

Metabolic and Endocrine Alterations Following Endotoxin Administration in Normal and Diabetic Rats

Discussion

Poster Presentations

Protection of Myocardial Structure in Hemorrhagic Shock

On Lung Morphology in Shock

Endogenous Fuel Utilization of Heart, Diaphragm and Liver in Cardiogenic Shock

Electrophysiologic Investigation of Brain Function in Endotoxin Shock

Catecholamines, Cyclic AMP and Metabolic Substrates after Anaphylaxis in the Rat

Catecholamines, cyclic AMP and Metabolic Substrates in Monkeys Subjected to Cytotropic Anaphylaxis

Morphological Study of Rabbits Myocardium in Endotoxin Shock

Effect of Fasting and Hemorrhagic Hypotension on Nickel Content of Different Organs in the Rat

Endorphins in the Pathophysiology of Hemorrhagic Shock

Changes in ACTH, STH, TSH, Prolactin, Thyroxine and Triiodthyronine during Endotoxin Shock in Rats

Electron Microscope Study of Cerebral Microcirculation in Rabbits during Endotoxin Shock

Regulation of Gluconeogenic Intermediates in Endotoxic and Septic Rat Livers

Hypertonic NaCl Infusions in the Treatment of Hypovolemic Shock: A Surprising Effect

Correlation between Liver Uptake of 14C-Endotoxin and 3H-Dexamethasone Binding in High Responder and Low Responder Mice

Coagulation Studies on Thoracic Duct Lymph in Hypovolemic Shock Dogs

Changes in the Biotransforming Activity of Hepatic Endoplasmic Reticulum in Rats Treated with E. Coli Endotoxin

The Effect of B. Coli Endotoxin on Gastric Evacuation and Intestinal Propulsion

Reactivity of the Adrenal Cortex, during Endotoxin Shock

Electrophoretic Mobility of Erythrocytes in Rabbits during Endotoxin Shock

Resetting of the Baroreceptor-Heart Rate Reflex in the Unanaesthetized Rat during and Following a Period of Hind Limb Ischaemia

Alterations of the Alveolar Surfactant in Haemorrhagic Shock

Intra-Aortic Infusions of Hypertonic NaCl do not Reverse Hypovolemic Shock

The Effect of Hepatic Mitochondrial Dysfunction on Gluconeogenesis in Hemorrhagic Shock

Changes in the Effective Renal Plasma Flow in Rabbits with Endotoxin Shock

In Vivo and In Vitro Effects of Endotoxin on Hepatic Membrane Transport of Na+, K+ and Ca2+

Protection of Myocardial Function in Hemorrhagic Shock

Kallikrein and Plasma Enzymes in Hemorrhagic Shock

The Role of the Blood-Brain Barrier in Endotoxic Shock. Experimental Studies on the Effects of Intravenous and Intracisternal Injections of Endotoxin

AV-Fistula Shock: A New Experimental Shock Model

Plasma Glucose and Insulin Levels in Rats during Endotoxin Shock

Two Cardiorespiratory Pattemis of Anaphylaxis in the Monkey

Hepatic Ultra-structural Changes during Splanchnic Shock in Dogs (Relation with Hepatic Microcirculation in Shock)

Changes in the Hepatic Micro-circulation during Splanchnic Shock Induced by In- and Outflow Occlusion of the Hepatic Vessels

Metabolic Changes in Burn Shock

Cerebrovascular Effects of Sustained Norepinephrine Infusion

Retransfusion Acidosis and Ventilation

Acid-Base Changes in the Blood of Rabbits in Endotoxin Shock

Anaerobic Metabolism and Oxygen Transport Indicators in Endotoxin Shock

Influence of BaCl2 on the Blood Flow in the Mesenteric Artery of Dogs under an Endotoxin Shock

Myofibrillar Alterations of Heart in Hemorrhagic Shock

Evolution of Lactacidemia during Treatment of Circulatory Shock

Experimental Researches on the Acid-Base Metabolism, Blood Gases and some Ventilatory Parameters within Exotoxic under Shock